REN-012 | Renibus Therapeutics

Metabolic Acidosis in Chronic Kidney Disease
Study evaluating the efficacy and safety of veverimer for the treatment of metabolic acidosis. The Nephrology Associates site was activated August 21, 2026 and is actively prescreening potential subjects.

APL2-FSG-319 | Biogen/Apellis

Focal Segmental Glomerulosclerosis (FSGS)
Sequential Phase 2/3 study evaluating pegcetacoplan (Empaveli), a C3 inhibitor, in patients with FSGS. The site was activated September 3, 2026 and is prescreening potential subjects.

LUMINA | Novartis

IgA Nephropathy (IgAN)
Clinical trial evaluating zigakibart, an APRIL inhibitor, in patients with IgA nephropathy. The site was activated in September 2026 and is prescreening potential subject